Establishing a Method for Laser Diffraction Particle Size Analysis of Lactose Powder

Lactose is one of the most common kinds of tablet excipients. The USP has clear regulations on raw materials particle sizing by laser diffraction method, such as the structure and principle of the instrument, the specific method of dry and wet dispersions, the factors in the measurement process, etc. However, for specific lactose, there is no related instruction on how to choose the dispersive pressure and how to evaluate the results of dry and wet methods. This note carried out a systematic research on lactose particle size distribution measurement in accordance with the USP and the ISO 13320.

Product:
Bettersizer 2600

Industry:
Pharmaceuticals

Sample:
Lactose

Measurement type:
Particle Size

Measurement by technology:
Laser Diffraction