Particle Sizing with Dry Dispersion Can Be the Best Choice for Pharmaceutical Analysis

This paper looks at laser diffraction technology which when initially conceived only measured particle size by diluting a sample with a suitable diluent and pumped the mix through a sample measuring cell. It explains how the move away from using solvents encouraged the use of measuring sample dry rather than wet and explains what the barriers to dry measurement were and how they were overcome during a period of 25 years. 

Pharmaceutical powders are generally considered to be some of the most cohesive a particle scientist will come across and are generally very demanding when using the wet method. In this paper, we will demonstrate how a modern dry laser diffraction is able to analyse these cohesive samples and achieve reliable repeatable results with an eco-friendlier method.

Product：

Bettersizer 2600

Industry:

Pharmaceuticals

Sample:

Microcrystalline Cellulose, Sodium Starch Glycolate, Dextrin,

Cetirizine Hydrochloride, Ticagrelor, Omeprazole,

Flunarizine Hydrochloride, Magnesium Stearate, Amlodipine Besylate

Measurement Type：

Particle Size

Measurement by Technology：